Researchers at the Mayo Clinic in the United States have discovered a new method that can detect and remove potentially dangerous stem cells to make stem cell therapy safer. Induced pluripotent stem cells (iPSCs) are obtained by reprogramming cells from adult tissues and have properties similar to embryonic stem cells, that is, they can differentiate into any desired cell type without limitation, such as skin Cells, brain cells, lung cells and heart cells. However, during the differentiation process, some residual pluripotent cells or embryonic-like cells may continue to exist and cause tumors to develop. Related research papers were recently published in Stem Cells Translational Medicine.
Dr. Timothy Nelson, the corresponding author of the paper, said, "Pluripotent stem cells have great promise in the field of regenerative medicine, but the risk of uncontrolled cell growth will continue to prevent people from using them as a treatment."
Using mouse model animals, Mayo Clinic researchers used a chemotherapeutic drug to pre-treat stem cells, which can selectively destroy the DNA of these stem cells, thereby effectively killing these tumor-forming cells. Dr. Nelson said that all the damaged cells died, and the chemotherapy drugs did not affect healthy cells.
The co-author of the paper, Dr. Alyson Smith, said, "The dual goal of building new therapies: stem cell-based regenerative therapy can help improve disease outcomes while also ensuring safety. This study outlines a strategy so that stem cell therapy can be more effective for our patients Safe, and at the same time ensure their therapeutic effect, so they can overcome the obstacles faced when applying these treatments to the clinic. "
Dr. Andre Terzic, co-author of the paper, said, "By taking advantage of the potential of regenerative medicine, we will be able to provide patients with more definitive treatments."
Researchers are continuing to optimize and improve stem cell therapy. They are discovering that stem cells may have more functions than people thought, which means they can be used to treat more diverse diseases, injuries and congenital abnormalities.
Rubber Grommets are essentially rubber molded parts which are placed around drilled or punched holes to an opening in a surface. Rubber grommets mechanically eliminate sharp edges providing a cushion of protection for the items which passes through the surface material from tearing or breaking wire, cable, tubing, piping, hoses, air lines, rope, etc, add aesthetic value to your applications. In addition, many grommets also serve as seals.
Rubber Grommets
Custom Rubber Grommets ,Rubber Wire Grommets,Silicone Rubber Grommet,Colored Rubber Grommet
Xiamen The Answers Trade Co.,Ltd. , https://www.answerssilicone.com